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Molekulare Diagnostik

PentaBase

Wir führen die SensiScreen® Ready-to-use CE-IVD Assays von PentaBase.

Da unser Sortiment in diesem Bereich sehr komplex ist, zögern Sie bitte nicht uns zu kontaktieren!

 SEITE IST IM ENTSTEHEN - ASSAYS ARE SOON AVAILABLE!


Kategorien:

 Colo Rectal Cancer (CRC)

KRAS

NRAS

BRAF V600

  Lung Cancer (NSCLC)

EGFR

 Melanoma

BRAF V600

 

  SensiScreen instruction.pdf

  Quick guide Ready-to-use.pdf

There are two types of assays available:

  1. SensiScreen® Ready-to-use CE-IVD Assays: SensiScreen® Ready-to-use assays are pre-dispensed in PCR strips and require only addition of patient DNA for somatic mutation testing.
  2. SensiScreen® Dispense Ready CE-IVD Mixes: SensiScreen® Dispense Ready CE-IVD Mixes include all reagents for somatic mutation testing except plastic ware to be used with the real-time PCR system of choice.

Overview of mutations detected by SensiScreen®

SensiScreen® assays detect the most common somatic mutations present in KRAS, NRAS, BRAF and EGFR. Furthermore, a range of new assays is expected to be added to the portfolio in 2017.

BRAF mutations detected by SensiScreen®

 

Assay CDS mutation Amino acid mutation Cosmic ID
BRAF exon 15 c.1799_1800TG>AT Val600Asp (V600D) COSM477
c.1799T>A Val600Glu (V600E) COSM476
c.1798_1799GT>AA Val600Lys (V600K) COSM473
c.1798_1799GT>AG Val600Arg (V600R) COSM474

ahn

brand

eppendorf

gilson

mettler toledo

heidolph

neolab

satorius

systec

thermo scientific

zeiss